Scrumhalf Embrose Papier will make his Springbok debut against Scotland at Murrayfield on Saturday (19h20).
Duane Vermuelen moves back to No 8 in place of the injured Warren Whiteley, while Pieter-Steph Du Toit will pack down at blindside flank again, moving from lock.
Whiteley is struggling with a calf strain and because he also won’t be ready for next week’s last tour match in Cardiff in Wales, it was decided to withdraw him from the rest of the tour.
15 Willie le Roux, 14 S’bu Nkosi, 13 Jesse Kriel, 12 Damian de Allende, 11 Aphiwe Dyantyi, 10 Handre Pollard, 9 Embrose Papier, 8 Duane Vermeulen, 7 Pieter-Steph du Toit, 6 Siya Kolisi (captain), 5 Franco Mostert, 4 RG Snyman, 3 Frans Malherbe, 2 Malcolm Marx, 1 Steven Kitshoff
Substitutes: 16 Bongi Mbonambi, 17 Thomas du Toit, 18 Vincent Koch, 19 Lood de Jager, 20 Francois Louw, 21 Ivan van Zyl, 22 Elton Jantjies, 23 Cheslin Kolbe.